Whereas energy function in the aging brain and their related neurodegenerative diseases has been explored in some detail, there is limited knowledge about molecular mechanisms and brain networks of energy metabolism during infancy and childhood.In this review we describe current insights on physiological brain energetics at prenatal and neonatal st
Optogenetics and chemogenetics are emerging neuromodulation techniques that have attracted significant attention in recent years.These techniques enable the precise control of specific neuronal types and neural circuits, allowing researchers to investigate the cellular mechanisms underlying depression.The advancement in these techniques has signifi
Neural stem cells (NSCs) in the adult mammalian brain serve as a reservoir for the generation of new neurons, oligodendrocytes, and astrocytes.Here, we use single-cell RNA sequencing to characterize adult NSC populations and examine the molecular identities and heterogeneity of in vivo NSC populations.We find that cells hindigyanvishv.com in the NS
Abstract.Over the past decade, mitochondrial dysfunction has been investigated as a key contributor to acute and chronic kidney disease.However, the precise molecular mechanisms linking mitochondrial damage to kidney disease remain elusive.The recent insights into the cyclic guanosine monophosphate-adenosine monophosphate (GMP-AMP) synthetase (cGAS